HCID 13133032, compound → HCID 13133047, compound

Participants

Reaction Steps

1-Methyl-2-isocyanato-3-phenyl-5-chloroindole (3.0 g) is heated at 100°-120° C. in an oil bath for 4 hours. Dimethylformamide (10 ml) is added to the reaction mixture and then refluxed for 30 minutes. After cooling, precipitates are separated by filtration and washed with ethanol to give 2.5 g of 7-methyl-10-chloro-7H-indolo(2,3-c)isoquinolin-5(6H)-one, melting point>300° C.

Provenance & Evidence