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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 444225Generated: October 31, 2026

2-Methoxyphenethylamine → HCID 12877856, compound

https://huagongshe.com/reaction/444225

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyphenethylamineHCID 74896—
ReactantHCID 12529024HCID 12529024—
ProductHCID 12877856HCID 12877856—

Reaction Conditions

Temperature60 °C

Reaction Steps

A mixture of 2-methoxyphenethylamine (0.91 g, 6 mmole) and (S) -2-(2,3-epoxy-1-propoxy)-3-cyanopyridine (1.05 g, 6 mmole) was heated at 60° C. for 18 hr. Upon cooling, the material solidified. Recrystallization from toluene afforded (S)-2-[3-(2-methoxyphenethylamino)-2-hydroxy-1-propoxy]-3-cyanopyridine (m.p. 97°-99°).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04263307
Source datasetuspto-grants-1981_04
ORD IDord-7d20f9033a4048f7b536c6941b169486
Source noteuspto-grants-1981_04