Acetone → HCID 13014066, compound

HRID 444226Notes

Reaction equation

HRID 444226 reaction equation
[CH3:1][C:2]([CH3:4])=O.[NH:5]([C:7]1[S:11][N:10]=[C:9]([C:12]([Cl:15])([Cl:14])[Cl:13])[N:8]=1)[NH2:6]>>[Cl:15][C:12]([Cl:13])([Cl:14])[C:9]1[N:8]=[C:7]([NH:5][N:6]=[C:2]([CH3:4])[CH3:1])[S:11][N:10]=1

Participants

3

Reactant 2

HCID 180AcetoneHCID 13014065HCID 13014065, compound

Product 1

HCID 13014066HCID 13014066, compoundYield 79%

Procedure

A mixture of 5 ml (3.9 g, 0.068 mole) acetone and 2.4 g (0.01 mole) 5-hydrazino-3-trichloromethyl-1,2,4-thiadiazole was heated 0.5 hour on a steam bath. The solid that was left after evaporation of the excess acetone was recrystallized from ligroin to yield 0.95 g (mp. 75°-77° C.). A second crop of 1.2 g (mp. 66° C.) was obtained after concentration of the solvent. Total yield was 2.15 g (79% yield).

Workup

  1. temperaturewas heated 0.5 hour on a steam bath
  2. waitThe solid that was left
  3. customafter evaporation of the excess acetone
  4. customwas recrystallized from ligroin
  5. customto yield 0.95 g (mp. 75°-77° C.)
  6. customA second crop of 1.2 g (mp. 66° C.) was obtained after concentration of the solvent

Sources & evidence

ORD record
ord-fc9a249ee6e84b8a957b2ac740c23cbb
Source dataset
uspto-grants-1981_04
Patent number
US04263312

Reaction notes

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