Bromine → HCID 178516871, compound

HRID 444231Notes

Reaction equation

HRID 444231 reaction equation
[Br:1]Br.[F:3][C:4]1[CH:5]=[C:6]2[C:12](=[CH:13][CH:14]=1)[C:10](=[O:11])[CH:9]=[C:8]([OH:15])[C:7]2=[O:16]>C(Cl)(Cl)Cl>[Br:1][C:9]1[C:10]([C:12]2[C:6]([C:7](=[O:16])[C:8]=1[OH:15])=[CH:5][C:4]([F:3])=[CH:14][CH:13]=2)=[O:11]

Participants

4

Reactant 2

HCID 24408BromineHCID 178516610HCID 178516610, compound

Product 1

HCID 178516871HCID 178516871, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

A solution of bromine (12.5 g), in chloroform (50 ml) was added to a stirred suspension of 6-fluoro-3-hydroxynaphtho-1,4-quinone (12.5 g; 0.065 mole) in chloroform (50 ml) over 15 mins. During the addition the mixture became a clear dark red solution. Stirring was continued for a further 4 hours and a yellow solid which had been deposited as crystals was filtered off, washed with ice-cold chloroform and dried. Yield 13.95 g (80%), mp 183° C. (CHCl3).

Workup

  1. additionDuring the addition the mixture
  2. filtrationwas filtered off
  3. washwashed with ice-cold chloroform
  4. customdried

Sources & evidence

ORD record
ord-c636ba5a738f4cdd895898dc6c36bbd6
Source dataset
uspto-grants-1981_04
Patent number
US04263309

Reaction notes

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