Acetohydrazide → HCID 53711504, compound

HRID 444254Notes

Reaction equation

HRID 444254 reaction equation
[CH3:1][O:2][N:3]=[C:4]([C:10]([CH3:12])=O)[C:5]([O:7][CH2:8][CH3:9])=[O:6].[C:13]([NH:16][NH2:17])(=[O:15])[CH3:14]>C(O)C>[CH3:1][O:2][N:3]=[C:4]([C:10](=[N:17][NH:16][C:13](=[O:15])[CH3:14])[CH3:12])[C:5]([O:7][CH2:8][CH3:9])=[O:6]

Participants

4

Reactant 2

HCID 14039AcetohydrazideHCID 43493Ethyl (2Z)-2-methoxyimino-3-oxo-butanoate

Product 1

HCID 53711504HCID 53711504, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of ethyl 2-methoxyiminoacetoacetate (a mixture of syn and anti isomer) (226.6 g.) and acetohydrazide (78.5 g.) in ethanol (500 ml.) was stirred for 1.5 hours at ambient temperature. Precipitates were collected by filtration, washed with ethanol and ether and dried to give ethyl 2-methoxyimino-3-acetylhydrazonobutyrate (a mixture of syn and anti isomers) (155.7 g.), mp 190° to 191.5° C.

Workup

  1. customPrecipitates
  2. filtrationwere collected by filtration
  3. washwashed with ethanol and ether
  4. customdried

Sources & evidence

ORD record
ord-0ab99f3439ab4372a27d90a31376534a
Source dataset
uspto-grants-1981_04
Patent number
US04263291

Reaction notes

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