Sodium Hydroxide → HCID 54447220, compound

HRID 444262Notes

Reaction equation

HRID 444262 reaction equation
[CH3:1][O:2][N:3]=[C:4]([C:10]1[CH:14]=[N:13][S:12][N:11]=1)[C:5]([O:7]CC)=[O:6].[OH-].[Na+]>>[CH3:1][O:2][N:3]=[C:4]([C:10]1[CH:14]=[N:13][S:12][N:11]=1)[C:5]([OH:7])=[O:6]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 53813605HCID 53813605, compound

Product 1

HCID 54447220HCID 54447220, compoundYield 94.3%

Procedure

Ethyl 2-methoxyimino-2-(1,2,5-thiadiazol-3-yl)acetate (anti isomer) (3.0 g.) was treated with 1 N aqueous solution of sodium hydroxide (16.8 ml.) according to a similar manner to that of Example 1(a)(5) to give 2-methoxyimino-2-(1,2,5-thiadiazol-3-yl)acetic acid (anti isomer) (2.46 g.), mp 110° to 111° C.

Sources & evidence

ORD record
ord-05d73863c87d4838ae3f5d97443abeab
Source dataset
uspto-grants-1981_04
Patent number
US04263291

Reaction notes

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