Hydrochloric Acid → HCID 13526432, compound

Participants

Reaction Steps

A suspension of 25 g. (0.064 mole) of 5,6-bis-(p-acetamidophenyl)-2,3-dihydroimidazo[2,1-b]thiazole, prepared as in Example 22, in 250 ml. of 6 N hydrochloric acid was refluxed with stirring under nitrogen for 1.75 hours. This solution was chilled, made alkaline with 10% aqueous sodium hydroxide and filtered. The precipitate was washed with a small amount of acetonitrile and recrystallized from acetonitrile with charcoal to give 5,6-bis(p-aminophenyl)-2,3-dihydroimidazo[2,1-b]thiazole, m.p. 205°-206.5° C.

Provenance & Evidence