Cyclopropylamine → HCID 3055554, compound

HRID 444307Notes

Reaction equation

HRID 444307 reaction equation
[CH3:1][C:2]1[S:3][C:4]([CH:7]=[CH:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[O:15][CH2:16][CH:17]2[O:19][CH2:18]2)=[N:5][N:6]=1.[CH:20]1([NH2:23])[CH2:22][CH2:21]1>C1(C)C=CC=CC=1>[CH3:1][C:2]1[S:3][C:4]([CH:7]=[CH:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[O:15][CH2:16][CH:17]([OH:19])[CH2:18][NH:23][CH:20]2[CH2:22][CH2:21]2)=[N:5][N:6]=1

Participants

4

Reactant 2

HCID 69828CyclopropylamineHCID 53934759HCID 53934759, compound

Product 1

HCID 3055554HCID 3055554, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

3.8 g (0.014 mole) of 2-methyl-5-[2-(2,3-epoxypropoxy)-styryl]-1,3,4-thiadiazole and 1.0 g (0.018 mole) of cyclopropylamine are reacted similarly to the Example relating to compound 3. 2.2 g (48% of theory) of yellow crystals, of melting point 144°-145° C., are obtained from toluene.

Sources & evidence

ORD record
ord-82df4568d9714749af082120dd416809
Source dataset
uspto-grants-1981_04
Patent number
US04263430

Reaction notes

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