Ethanol → Benzenamine, N-ethyl-2-nitro-4-(trifluoromethyl)-

HRID 444313Notes

Reaction equation

HRID 444313 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH2:15]([NH2:17])[CH3:16].[CH2:18](O)[CH3:19]>>[N+:12]([C:3]1[CH:4]=[C:5]([C:8]([F:11])([F:10])[F:9])[CH:6]=[CH:7][C:2]=1[NH:17][CH2:15][CH3:16])([O-:14])=[O:13].[NH2:12][C:3]1[C:4]([NH2:17])=[C:5]([C:8]([F:11])([F:10])[F:9])[CH:6]=[CH:7][C:2]=1[CH2:18][CH3:19]

Participants

5

Reactant 3

HCID 702EthanolHCID 6341EthylamineHCID 84624-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene

Product 2

HCID 121682Benzenamine, N-ethyl-2-nitro-4-(trifluoromethyl)-HCID 23464913HCID 23464913, compound

Procedure

At first, 3-nitro-4-ethylamino-benzotrifluoride is prepared from 4-chloro-3-nitrobenzotrifluoride and ethyl-amine according to Geman Offenlegungsschrift No. 2 018 232, Example 1), and the former product is catalytically reduced in ethanol to give the 3-amino-4-ethyl-amino-benzotrifluoride colorless crystals of a melting point of from 72° to 74° C.

Sources & evidence

ORD record
ord-7b985437671e401694ef245a25b5246d
Source dataset
uspto-grants-1981_04
Patent number
US04263441

Reaction notes

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