反应详情

To a solution of N-methyl-N-phenylthiocarbamyl chloride 79.6 g (0.43 m) in 250 ml dry ether, a solution of 39.5 g (0.86 m) methylhydrazine in 100 ml of dry ether was added dropwise with stirring below 10° C. The reaction temperature was allowed to increase to room temperature and filtered. The filtrate was evaporated to low volume and diluted with ~300 ml hexane. After stirring for a few hours the hexane layer was decanted. The hexane immiscible layer was reevacuated to remove organic solvents, giving the desired product, 70.0 g as a thick orange liquid.

1. filtrationfiltered
2. customThe filtrate was evaporated to low volume
3. additiondiluted with ~300 ml hexane
4. stirringAfter stirring for a few hours the hexane layer
5. customwas decanted
6. customto remove organic solvents