HCID 53952628, compound → HCID 54021173, compound

HRID 444412Notes

Reaction equation

HRID 444412 reaction equation
C([O:4][C@@H:5]1[C@@:29]2([CH3:30])[C:9](=[CH:10][CH:11]=[C:12]3[C@@H:28]2[CH2:27][CH2:26][C@@:25]2([CH3:31])[C@H:13]3[CH2:14][CH2:15][C@@H:16]2[C@H:17]([CH3:24])[CH2:18][CH2:19][CH2:20][CH:21]([CH3:23])[CH3:22])[CH2:8][CH2:7][CH2:6]1)(=O)C>[OH-].[K+]>[OH:4][C@@H:5]1[C@@:29]2([CH3:30])[C:9](=[CH:10][CH:11]=[C:12]3[C@@H:28]2[CH2:27][CH2:26][C@@:25]2([CH3:31])[C@H:13]3[CH2:14][CH2:15][C@@H:16]2[C@H:17]([CH3:24])[CH2:18][CH2:19][CH2:20][CH:21]([CH3:22])[CH3:23])[CH2:8][CH2:7][CH2:6]1

Participants

3

Reactant 1

HCID 53952628HCID 53952628, compound

Product 1

HCID 54021173HCID 54021173, compound

Reagents, catalysts & solvents 1

HCID 14797Potassium HydroxideSolvent

Procedure

A solution of 1α-acetoxy-5,7-cholestadiene (11, R is acetyl, 8.3 mg) and 5% methanolic potassium hydroxide (10 ml) was allowed to stand at room temperature under an atmosphere of nitrogen overnight. Work-up of the reaction mixture in the usual way gave 1α-hydroxy-5,7-cholestadiene.

Sources & evidence

ORD record
ord-5e1daef96a254fd5b36b82b3a86b081f
Source dataset
uspto-grants-1981_04
Patent number
US04264512

Reaction notes

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