3-[(3-Methoxypyridin-2-yl)oxy]propane-1,2-diol → 2-[(2-Ethoxy-2-methyl-1,3-dioxolan-4-yl)methoxy]-3-methoxypyridine

Beteiligte Stoffe

Reaktionsschritte

2 drops of trifluoroacetic acid are added to a solution of 62 g of 3-(3-methoxy-2-pyridyloxy)-1,2-propanediol in 350 ml of triethyl orthoacetate and the mixture is left to stand for 3 hours at 20°-30°. On evaporation, crude 2-ethoxy-5-(3-methoxy-2-pyridyloxymethyl)-2-methyl-1,3-dioxolane is obtained in the form of an oil, which is used without purification.

Herkunft & Nachweise