HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Chlorotrimethylsilane → 2-(2-Acetoxy-3-chloro-propoxy)-3-methoxy-pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Chlorotrimethylsilane | HCID 6397 | — |
| Edukt | 2-[(2-Ethoxy-2-methyl-1,3-dioxolan-4-yl)methoxy]-3-methoxypyridine | HCID 13195075 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 2-(2-Acetoxy-3-chloro-propoxy)-3-methoxy-pyridine | HCID 13195076 | — |
Reaktionsschritte
45 ml of trimethylchlorosilane are added to a mixture of 85 g of 2-ethoxy-5-(3-methoxy-2-pyridyloxymethyl)-2-methyl-1,3-dioxolane in 500 ml of methylene chloride and the mixture is stirred for one hour at 20°-30°. Complete evaporation under reduced pressure yields crude 2-(2-acetoxy-3-chloro-propoxy)-3-methoxy-pyridine in the form of an oil, which is used without purification.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04264599 |
| Quelldatensatz | uspto-grants-1981_04 |
| ORD ID | ord-7954d72259c94326a872eba2df1e1d41 |
| Quellennotiz | uspto-grants-1981_04 |