HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl N-cyanodithioiminocarbonate → N-cyano-N'-[2-((3-methoxy-2-pyridyl)methylthio)ethyl]S-methylisothiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl N-cyanodithioiminocarbonate | HCID 66289 | — |
| Reactant | 2-{[(3-Methoxypyridin-2-yl)methyl]sulfanyl}ethan-1-amine | HCID 12951535 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-cyano-N'-[2-((3-methoxy-2-pyridyl)methylthio)ethyl]S-methylisothiourea | HCID 20474175 | 72.4% |
Reaction Steps
A solution of 2-[2-aminoethylthiomethyl]-3-methoxypyridine (2.1 g) in ethanol (15 ml) was added over one hour to a stirred solution of dimethyl N-cyanodithioimidocarbonate (1.5 g) in ethanol (15 ml). The mixture was allowed to stand overnight and nitrogen was bubbled through for one hour. The crystalline precipitate was recrystallised from ethanol/ether to yield N-cyano-N'-[2-((3-methoxy-2-pyridyl)methylthio)ethyl]-S-methylisothiourea (2.2 g), m.p. 102°-103°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04264608 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-3710440115794858b3e40f1715e2a966 |
| Source note | uspto-grants-1981_04 |