Ammonia → HCID 178514025, compound

HRID 444554Notes

Reaction equation

HRID 444554 reaction equation
CSC[N:4]1C(S)=NN=N1.C1(C)C=CC(S(O)(=O)=O)=CC=1.C(OC(=O)CN)C1C=CC=CC=1.C1(C)C=CC(S(O)(=O)=O)=CC=1.C(OC(=O)CCN)C1C=CC=CC=1.C([O:64][C:65]([CH2:67][N:68]1[C:72]([SH:73])=[N:71][N:70]=[N:69]1)=O)C1C=CC=CC=1.N>>[C:65]([CH2:67][N:68]1[C:72]([SH:73])=[N:71][N:70]=[N:69]1)(=[O:64])[NH2:4]

Participants

6

Reactant 5

HCID 222AmmoniaHCID 6451311O-benzylglycine toluene-p-sulphonateHCID 135021004-Methylbenzene-1-sulfonic acid--benzyl beta-alaninate (1/1)HCID 178503853HCID 178503853, compoundHCID 178521271HCID 178521271, compound

Product 1

HCID 178514025HCID 178514025, compound

Procedure

The reactions described in Reference Example 10 (1) and (2) were carried out using glycine benzyl ester p-toluenesulfonate in lieu of β-alanine benzyl ester p-toluenesulfonate to prepare 1-benzyloxycarbonylmethyl-1H-tetrazole-5-thiol, which was then converted with alcoholic ammonia into the captioned compound.

Sources & evidence

ORD record
ord-8e66aadce325444aa29bf73cbfc3b989
Source dataset
uspto-grants-1981_04
Patent number
US04264595

Reaction notes

Loading…