HCID 66935227, compound → HCID 66935220, compound

Participants

Reaction Steps

To a solution of 2-[1-(benzylamino)cyclobutyl]-N-(tert-butoxycarbonyl)ethylamine (117 mg, 0.384 mmol) in EtOH (5 mL) was added 10% Pd—C (35 mg) and the mixture was stirred under H2 gas 5 kgf/cm2 at room temperature for 5 h. The mixture was filtered, and the filtrate was concentrated in vacuo. The distillation of the residue gave the title compound as a colorless solid (76.0 mg, 92%). 1H-NMR (400 MHz, DMSO-d6) δ 1.37 (9H, s), 1.49-1.58 (2H, m), 1.62-1.77 (4H, m), 1.82-1.91 (2H, m), 2.92-3.01 (2H, m), 6.78 (1H, t, J=5.5 Hz).

Provenance & Evidence