HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(4-Chloro-2-methylphenyl)boronic acid → 3-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (4-Chloro-2-methylphenyl)boronic acid | HCID 5017600 | — |
| Edukt | Methyl 3-amino-6-bromo-5-(trifluoromethyl)picolinate | HCID 58964428 | — |
| Produkt | 3-Amino-6-(4-chloro-2-methyl-phenyl)-5-trifluoromethyl-pyridine-2-carboxylic acid | HCID 68169540 | — |
Reaktionsschritte
This compound was prepared from 3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester (Intermediate A4) and 4-chloro-2-methylphenylboronic acid analogously to Intermediate H; LC-MS Rt=1.53 mins, [M+H]+ 331 (Method 2 min LC_v002).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08476269B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-6e675906c96b4adb9caa95d8fc401b9b |
| Quellennotiz | uspto-grants-2013_07 |