4-Bromo-3,5-dimethylphenol → 4-(4-Bromo-3,5-dimethylphenoxy)-2-methylbutan-2-ol

HRID 445110Notes

Reaction equation

HRID 445110 reaction equation
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([OH:9])=[CH:4][C:3]=1[CH3:10].CC1C=CC(S(O[CH2:22][CH2:23][C:24]([OH:27])([CH3:26])[CH3:25])(=O)=O)=CC=1>>[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([O:9][CH2:22][CH2:23][C:24]([CH3:26])([OH:27])[CH3:25])=[CH:4][C:3]=1[CH3:10]

Participants

3

Reactant 2

HCID 819704-Bromo-3,5-dimethylphenolHCID 140012952-Methyl-4-[(4-methylbenzenesulfonyl)oxy]butan-2-ol

Product 1

HCID 679729214-(4-Bromo-3,5-dimethylphenoxy)-2-methylbutan-2-olYield 101.9%

Procedure

According to the method of (Example 10) <Step 2>, from 4-bromo-3,5-dimethylphenol (3.60 g) and 3-hydroxy-3-methylbutyl 4-methylbenzene sulfonate (5.09 g), the subject compound (5.24 g) was obtained as a colorless oil.

Sources & evidence

ORD record
ord-72ad7bca23034e38a90e9c015f91657d
Source dataset
uspto-grants-2013_07
Patent number
US08476287B2

Reaction notes

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