HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl carbamate → HCID 3698650, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl carbamate | HCID 77922 | — |
| Reactant | HCID 3698650 | HCID 3698650 | — |
| Product | HCID 3698650 | HCID 3698650 | — |
| Product | 2-Boc-2-azabicyclo[2.2.2]octane-6-one | HCID 67234017 | — |
Reaction Steps
2-benzyl-2-azabicyclo[2.2.2]octan-6-ol is prepared using a method analogous to that described in U.S. Ser. No. 05/147,873. 2-benzyl-2-azabicyclo[2.2.2]octan-6-ol is debenzylated and subsequently protected as the tert-butyl carbamate using procedures analogous to those described in Example 1. Oxidation of the resulting intermediate alcohol using the Swern protocol affords the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08476295B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-550a278d01cb41b49ae6198551fe05d1 |
| Source note | uspto-grants-2013_07 |