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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 445124Generated: October 29, 2026

4-Methylbenzaldehyde → 4-(4-(((1SR,4SR,7RS)-2-(4-methylbenzyl)-2-azabicyclo[2.2.1]heptan-7-yl)amino)phenyl)-1,2,5-oxadiazol-3-amine

https://huagongshe.com/reaction/445124

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzaldehydeHCID 7725—
Reactant4-(4-((1SR,4SR,7RS)-2-azabicyclo[2.2.1]heptan-7-ylamino)phenyl)-1,2,5-oxadiazol-3-amineHCID 67235677—
Product4-(4-(((1SR,4SR,7RS)-2-(4-methylbenzyl)-2-azabicyclo[2.2.1]heptan-7-yl)amino)phenyl)-1,2,5-oxadiazol-3-amineHCID 53247054—

Reaction Steps

Reaction of Intermediate 40 with 4-methylbenzaldehyde affords the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08476295B2
Source datasetuspto-grants-2013_07
ORD IDord-216e3f9a4aa744c986efe0284a0d3e43
Source noteuspto-grants-2013_07