反应详情

To a solution of 200 mg (0.456 mmol) 1-(2-hydroxy-2-phenyl-ethyl)-4-(4-isopropyl-phenyl)-6-prop-2-ynyloxy-1H-quinazolin-2-one in 2 ml acetone are added 0.17 ml (0.45 mmol) Jones reagent. After stirring for 30 minutes at rt aqueous work up followed by recrystallisation from ethyl acetate yields 4-(4-isopropyl-phenyl)-1-(2-oxo-2-phenyl-ethyl)-6-prop-2-ynyloxy-1H-quinazolin-2-one.

1. customup followed by recrystallisation from ethyl acetate