反应详情

Add 2-bromothiophene-3-carbonyl chloride (540 mg, 2.39 mmol) to a solution of aqueous ammonia (25%, 3 mL, 17.44 mmol) with stirring. Stir the mixture for 30 minutes. Concentrate the mixture. Collect the resulting precipitate via filtration and wash the solids with water. Dry the white precipitate in vacuo to obtain the title compound (450 mg, 2.17 mmol).

1. stirringStir the mixture for 30 minutes
2. concentrationConcentrate the mixture
3. customCollect the resulting precipitate
4. filtrationvia filtration
5. washwash the solids with water
6. customDry the white precipitate in vacuo