Hydrochloric Acid → HCID 86664465, compound

Participants

Reaction Conditions

Reaction Steps

The compound (16.5 g) obtained in Example 31(1) was dissolved in 52 mL of ethanol and an aqueous 2N sodium hydroxide solution (10 mL) was added thereto, followed by stirring at 70° C. for 2 hours. After completion of the reaction, the reaction solution was neutralized by adding an aqueous 5N hydrochloric acid solution (5.2 mL). To a separately prepared water 130 mL solution of calcium chloride (1.45 g), the neutralized solution was slowly added at 0° C., and the precipitated solid was filtered and washed with ethanol and water to obtain the title compound (14.2 g) having the following physical properties.

Provenance & Evidence