Isopropyl isocyanate → HCID 59536421, compound

Participants

Reaction Steps

To a solution of 1-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline (70 mg, 0.252 mmol, example 9 (step 3) and DIEA (44 μL, 0.252 mmol) in DCM (1.6 mL) was added 2-isocyanatopropane (25 μL, 0.252 mmol). The resulting mixture was reacted under the same conditions as described for example 10 to give the title compound as a white solid. MS (ESI, positive ion) m/z: 363 (M+H).

Provenance & Evidence