4-Fluorophenyl isocyanate → HCID 46095902, compound

Participants

Reaction Steps

To a solution of 1-(4-chlorophenyl)-1,2,3,4-tetrahydroisoquinoline (150 mg, 615 μmol) in CH2Cl2 (2.0 mL) at RT was added 1-fluoro-4-isocyanatobenzene (85.8 μL, 739 μmol). The reaction was stirred 3 h and then directly purified by reverse phase HPLC to give the title compound as a white solid. MS (ESI pos. ion) m/z: 381 (M+1).

Provenance & Evidence