HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 2-Hydroxy-8-phenyloctanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 7-Phenylheptanal | HCID 14840064 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Hydroxy-8-phenyloctanenitrile | HCID 53925388 | — |
Reaction Steps
A two-phase mixture of ethyl acetate (30 mL) and water (35 mL) containing 7-phenylheptanal (5.2 g) and KCN (7.1 g) was stirred vigorously at room temperature for 24 h. The layers were separated and the aqueous phase was washed with water, dried (Na2SO4) and concentrated to yield 2-hydroxy-8-phenyloctanenitrile as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08476302B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-872fdf09e61141fb83faf2e123a6fc6b |
| Source note | uspto-grants-2013_07 |