3-(1-Methylethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → HCID 49793270, compound

Participants

Reaction Steps

The title compound was synthesized in a similar manner as described for Example 1.1 using 8-bromo-1-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one (Intermediate A) and 3-isopropoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine (Stage 58.1.1) to give the title compound as a white solid. (HPLC: tR 2.30 min (Method A); M+H=429 MS-ES; 1H-NMR (d6-DMSO, 400 MHz) 8.99 (s, 1H), 8.33-8.28 (m, 1H), 8.28-8.23 (m, 1H), 8.16-8.08 (m, 2H), 8.02-7.96 (m, 1H), 7.61-7.55 (m, 1H), 7.38-7.33 (m, 1H), 4.84-4.73 (m, 1H), 3.89 (s, 3H), 3.58 (s, 3H), 1.96 (s, 3H), 1.33 (d, 6H))

Provenance & Evidence