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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 445666Generated: October 30, 2026

2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol → 8-bromo-1-[1-(2-hydroxy-ethyl)-3-methyl-1H-pyrazol-4-yl]-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

https://huagongshe.com/reaction/445666

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanolHCID 55284690—
Reactant8-Bromo-1-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-oneHCID 59619739—
Product8-bromo-1-[1-(2-hydroxy-ethyl)-3-methyl-1H-pyrazol-4-yl]-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-oneHCID 59619999—

Reaction Steps

Alternatively, the title compound was synthesized in a similar manner as described for intermediate A starting from 2-(4-amino-3-methyl-pyrazol-1-yl)-ethanol (Stage 103.1.2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08476294B2
Source datasetuspto-grants-2013_07
ORD IDord-e7b6374fcb754346ab42df303911586b
Source noteuspto-grants-2013_07