HCID 59619695, compound → HCID 59619832, compound

Participants

Reaction Steps

The title compound was synthesized in a similar manner as described for Example 1.1 using 8-bromo-1-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one (Intermediate A) and 3-(2-fluoro-1-fluoromethyl-ethoxy)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine (Stage 182.1.1) to give the title compound as a white solid. (HPLC: tR 2.31 min (Method A); M+H=465 MS-ES; 1H-NMR (d6-DMSO, 400 MHz) 8.99 (s, 1H), 8.40-8.37 (m, 1H), 8.36-8.33 (m, 1H), 8.16-8.10 (m, 2H), 8.02-7.97 (m, 1H), 7.59-7.54 (m, 2H), 5.24-5.08 (m, 1H), 4.91-4.65 (m, 4H), 3.90 (s, 3H), 3.58 (s, 3H), 1.96 (s, 3H))

Provenance & Evidence