HCID 59619737, compound → HCID 59619838, compound

Participants

Reaction Steps

The title compound was synthesized in a similar manner as described for Example 1.1 using 8-bromo-1-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one (Intermediate A) and N-methyl-2-[5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-3-yl]-acetamide (Stage 228.1.1) to give the title compound as an off-white foam. (HPLC: tR 1.97 min (Method A); M+H=442 MS-ES; 1H-NMR (d6-DMSO, 400 MHz) 8.99 (s, 1H), 8.55-8.53 (m, 1H), 8.45-8.43 (m, 1H), 8.16-8.12 (m, 2H), 8.07-8.01 (m, 1H), 7.95-7.90 (m, 1H), 7.77-7.74 (m, 1H), 7.59-7.57 (m, 1H), 3.92 (s, 3H), 3.58 (s, 3H), 3.51 (s, 2H), 2.60 (d, 3H), 1.95 (s, 3H))

Provenance & Evidence