HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 2-(5-Bromo-pyridin-3-yl)-N-methyl-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2-(5-Bromopyridin-3-yl)acetic acid | HCID 2802539 | — |
| Product | 2-(5-Bromo-pyridin-3-yl)-N-methyl-acetamide | HCID 54236812 | — |
Reaction Steps
The title compound was synthesized in a similar manner as described for Example 103 using (5-bromo-pyridin-3-yl)-acetic acid (ABCR, Karlsruhe, Germany, 1.815 mmol) and 8 M methylamine in EtOH (Aldrich, Buchs, Switzerland, 7.26 mmol) to give the title compound as an off-white solid. (HPLC: tR 1.74 min (Method A); M+H=229, 231 MS-ES)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08476294B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-2a07b27fc62142d5a8c6f5ad95515fb3 |
| Source note | uspto-grants-2013_07 |