HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Borane → HCID 45110549, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Borane | HCID 6331 | — |
| Edukt | 1-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione | HCID 9887588 | — |
| Produkt | HCID 45110549 | HCID 45110549 | — |
Reaktionsschritte
Optionally, 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one or its derivative is reduced by using a suitable borane containing reducing agent as earlier, in absence or presence of an acid in a suitable solvent to get 3-hydroxy-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl) butan-1-one.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08476437B2 |
| Quelldatensatz | uspto-grants-2013_07 |
| ORD ID | ord-ee1854dac9cd4e29afd75e2b0939ed97 |
| Quellennotiz | uspto-grants-2013_07 |