Dimethylformamide → 6-[(Dimethylamino)methylene]-2-ethoxycyclohex-2-en-1-one

Participants

Reaction Conditions

Reaction Steps

3.4 g (0.02 mmol) of 2-ethoxycyclohex-2-en-1-one were dissolved in 30 mL of dry dimethylformamide and 30 mL (0.05 mmol) of dimethylformamide dimethyl acetale were added. The solution was stirred at 60° C. for 2 hours. The solvent was then evaporated under vacuum, the residue triturated with diethyl ether and collected by filtration to give 6.6 g of the title compound (80% yield).

Provenance & Evidence