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HRID446389

反应详情

EQUATION

反应方程式

HRID 446389 的结构方程式

REACTANTS

反应物

3
结构：CO
HCID887

Methanol

CH4O

结构：C#CCCO[Si](C)(C)C(C)(C)C
HCID4304567

tert-Butyl[(but-3-yn-1-yl)oxy]dimethylsilane

C10H20OSi

结构：OCCCc1cccc(CO)c1
HCID55267680

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)[Si](C)(C)OCCC#Cc1cccc(CO)c1
HCID58168614

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：N
溶剂HCID222

Ammonia gas

H3N

PROCEDURE

实验过程

Prepared by the method of Aromatic Intermediate 18, step a using tert-butyldimethyl(but-3-ynyloxy)silane (0.92 g) in place of tert-butyl dimethyl(prop-2-ynyloxy)silane. The preparative HPLC conditions were changed to XBridge™, Gradient: 75-99% methanol in 0.2% aqueous ammonia to avoid cleavage of the silyl protecting group. Yield 0.79 g.