HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → Methyl 5-amino-2-thiophenecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 5-Aminothiophene-2-carboxylic acid | HCID 19433970 | — |
| Product | Methyl 5-amino-2-thiophenecarboxylate | HCID 7131725 | 114.5% |
Reaction Steps
5-Aminothiophene-2-carboxylic acid (1.00 g, 5.78 mmol) instead of 2-formylbenzoic acid and methyl iodide (1.44 mL, 23.1 mmol) instead of benzyl bromide were used to give the title compound (1.04 g; yield, 97%) as a dark brown solid according to the method described in Example 3a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08476253B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-fa2cd6e428d64a7f88757c2881742763 |
| Source note | uspto-grants-2013_07 |