HCID 86663435, compound → HCID 86663437, compound

HRID 446527Notes

Reaction equation

HRID 446527 reaction equation
O=[CH:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([O:9][C:10]([CH3:13])([CH3:12])[CH3:11])=[O:8].[NH2:14][C:15]1[CH:20]=[CH:19][C:18]([C:21]([N:23]([CH3:36])[CH2:24][CH2:25][CH2:26][N:27]([CH3:35])[C:28](=[O:34])[O:29][C:30]([CH3:33])([CH3:32])[CH3:31])=[O:22])=[CH:17][CH:16]=1>>[C:30]([O:29][C:28]([N:27]([CH3:35])[CH2:26][CH2:25][CH2:24][N:23]([CH3:36])[C:21]([C:18]1[CH:19]=[CH:20][C:15]([NH:14][CH2:2][CH2:3][O:4][CH2:5][CH2:6][C:7]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:8])=[CH:16][CH:17]=1)=[O:22])=[O:34])([CH3:32])([CH3:31])[CH3:33]

Participants

3

Reactant 2

HCID 86663435HCID 86663435, compoundHCID 866634381246247-28-8

Product 1

HCID 86663437HCID 86663437, compoundYield 83%

Procedure

The compound (87 mg, 0.461 mmol) obtained in Example 28b and the compound (150 mg, 0.461 mmol) obtained in Example 28d were used to give the title compound (188 mg; yield, 83%) as a colorless oily substance according to the method described in Example 18b.

Sources & evidence

ORD record
ord-9832baf92a62409fbd7d522ee9d048c3
Source dataset
uspto-grants-2013_07
Patent number
US08476253B2

Reaction notes

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