Benzoic acid, 4-amino-, 1,1-dimethylethyl ester → tert-Butyl 4-({7-[(2-{4-[(biphenyl-2-ylcarbamoyl)oxy]piperidin-1-yl}ethyl)(methyl)amino]-7-oxoheptyl}amino)benzoate

Participants

Reaction Steps

The compound (94 mg, 0.195 mmol) obtained in Example 39b was used to give a crude aldehyde compound according to the method described in Example 4g. The resulting crude aldehyde compound and tert-butyl 4-aminobenzoate (62 mg, 0.293 mmol) were used to give the title compound (66 mg; yield, 52%) as a white solid according to the method described in Example 18b.

Provenance & Evidence