Trifluoroacetic acid → 3-({6-[(2-{4-[(Biphenyl-2-ylcarbamoyl)oxy]piperidin-1-yl}ethyl)(methyl)amino]-6-oxohexyl}amino)benzoic acid

Participants

Reaction Steps

The compound (80.0 mg, 0.124 mmol) obtained in Example 43a was dissolved in dichloromethane (6 mL), trifluoroacetic acid (1 mL) was added under ice cooling, and the mixture was stirred at room temperature under a nitrogen atmosphere for 1.5 hours. After the reaction was completed, the mixture was concentrated under reduced pressure to give a crude title compound.

Provenance & Evidence