tert-Butyl [3-(6-amino-1-oxo-3,4-dihydroisoquinolin-2(1H)-yl)propyl]methylcarbamate → 1-{2-[{6-[(2-{3-[(tert-Butoxycarbonyl)(methyl)amino]propyl}-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl)amino]hexanoyl}(methyl)amino]ethyl}piperidin-4-yl biphenyl-2-ylcarbamate

Participants

Reaction Steps

The compound (149 mg, 0.447 mmol) obtained in Example 61d and the compound (250 mg, 0.536 mmol) obtained in Example 4g were used to give the title compound (85 mg; yield, 24%) as a colorless oily substance according to the method described in Example 45b.

Provenance & Evidence