Sodium Hydroxide → HCID 58400589, compound

HRID 446629Notes

Reaction equation

HRID 446629 reaction equation
[C:1]([NH:5][CH2:6][CH2:7][CH2:8][S:9]([OH:12])(=[O:11])=[O:10])([CH3:4])([CH3:3])[CH3:2].[OH-].[Na+:14]>CO>[C:1]([NH:5][CH2:6][CH2:7][CH2:8][S:9]([O-:12])(=[O:10])=[O:11])([CH3:4])([CH3:2])[CH3:3].[Na+:14]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 111715633-(tert-Butylamino)propylsulfonic acid

Product 1

HCID 58400589HCID 58400589, compoundYield 93.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3-(tert-Butylamino)propylsulfonic acid (18 g) was added to a solution of sodium hydroxide (3.69 g, 0.092 mol) in methanol (300 mL). The mixture was stirred till become clear. The solvent was removed and the solid residue was dried in vacuum to give sodium 3-(tert-butylamino)propylsulfonate (18.7 g), as white microcrystals, decomposition at 170° C., 1H NMR (D2O) δ 1.08 (s, 9H), 1.80-1.90 (m, 2H), 2.64 (t, J=7.6 Hz, 2H), 2.91-2.96 (m, 2H); 13C NMR δ 24.4, 26.9, 39.8, 48.7, 49.6.

Workup

  1. customThe solvent was removed
  2. customthe solid residue was dried in vacuum

Sources & evidence

ORD record
ord-592473b3d198409498375d3538edbdb6
Source dataset
uspto-grants-2013_07
Patent number
US08480795B2

Reaction notes

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