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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 446833Generated: October 29, 2026

HCID 58392673, compound → (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-8-(3,3-Dimethyl-butyl)-4b,12-difluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a-dimethyl-4b,5,6,6a,6b,7,8,9,9a,10,10a,10b,11,12-tetradecahydro-4aH-8-aza-pentaleno[2,1-a]phenanthren-2-one

https://huagongshe.com/reaction/446833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58392673HCID 58392673—
Reactant(1S,2S,4R,8S,9S,11S,12R,13S,19S)-6-(cyclopropylmethyl)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-oneHCID 58392813—
Product(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-8-(3,3-Dimethyl-butyl)-4b,12-difluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a-dimethyl-4b,5,6,6a,6b,7,8,9,9a,10,10a,10b,11,12-tetradecahydro-4aH-8-aza-pentaleno[2,1-a]phenanthren-2-oneHCID 5839276469%

Reaction Steps

The title compound is prepared from compound 56 following the procedure described in Example 10 for the synthesis of compound 45.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481517B2
Source datasetuspto-grants-2013_07
ORD IDord-e566352083e046fea7cda05f21abf442
Source noteuspto-grants-2013_07