HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58392673, compound → (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-8-(3,3-Dimethyl-butyl)-4b,12-difluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a-dimethyl-4b,5,6,6a,6b,7,8,9,9a,10,10a,10b,11,12-tetradecahydro-4aH-8-aza-pentaleno[2,1-a]phenanthren-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58392673 | HCID 58392673 | — |
| Reactant | (1S,2S,4R,8S,9S,11S,12R,13S,19S)-6-(cyclopropylmethyl)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-azapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one | HCID 58392813 | — |
| Product | (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-8-(3,3-Dimethyl-butyl)-4b,12-difluoro-5-hydroxy-6b-(2-hydroxy-acetyl)-4a,6a-dimethyl-4b,5,6,6a,6b,7,8,9,9a,10,10a,10b,11,12-tetradecahydro-4aH-8-aza-pentaleno[2,1-a]phenanthren-2-one | HCID 58392764 | 69% |
Reaction Steps
The title compound is prepared from compound 56 following the procedure described in Example 10 for the synthesis of compound 45.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481517B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-e566352083e046fea7cda05f21abf442 |
| Source note | uspto-grants-2013_07 |