Sodium Iodide → HCID 58392699, compound

Participants

Reaction Conditions

Reaction Steps

In a closed vessel, a mixture of compound 165 (592 mg, 1.039 mmol) and sodium iodide (2181 mg, 14.55 mmol) in acetone (25 ml) is heated under microwave irradiation for 3 hours at 110° C. The reaction mixture is partitioned between AcOEt and a 5% solution of Na2S2O5. The organic phase is washed with brine, dried over Na2SO4 and filtered. The solvent is evaporated to give the title compound (495 mg, 100%).

Provenance & Evidence