Diethyl Ether → HCID 68579748, compound

Participants

Reaction Steps

To a stirred solution of 4-((S)-1-{2-[4-(2-phenoxy-phenylsulfamoyl)-benzoylamino]-acetyl}-pyrrolidine-2-carbonyl)-piperazine-1-carboxylic acid tert-butyl ester (0.115 g, 0.166 mmol) in dichloromethane (2 mL) 9 M hydrogen chloride in ethanol (0.2 mL) was added. The reaction mixture was stirred at room temperature for 2 h, then diethyl ether (20 mL) was added, the precipitated crystals were filtered, washed with diethyl ether and dried to yield 0.089 g (89%) of the title compound. MS (EI) 592.2 (MH+).

Provenance & Evidence