Glycine ethyl ester, hydrochloride → HCID 68577607, compound

HRID 446866Notes

Reaction equation

HRID 446866 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:21][C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=2)=[C:6]([NH:8][S:9]([C:12]2[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=2)(=[O:11])=[O:10])[CH:7]=1.Cl.[CH2:30]([O:32][C:33](=[O:36])[CH2:34][NH2:35])[CH3:31]>>[CH2:30]([O:32][C:33](=[O:36])[CH2:34][NH:35][C:16](=[O:17])[C:15]1[CH:19]=[CH:20][C:12]([S:9](=[O:10])(=[O:11])[NH:8][C:6]2[CH:7]=[C:2]([F:1])[CH:3]=[CH:4][C:5]=2[O:21][C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=2)=[CH:13][CH:14]=1)[CH3:31]

Participants

3

Reactant 2

HCID 2723640Glycine ethyl ester, hydrochlorideHCID 68493134HCID 68493134, compound

Product 1

HCID 68577607HCID 68577607, compound

Procedure

The title compound was prepared from 4-[5-fluoro-2-(4-fluoro-phenoxy)-phenylsulfamoyl]-benzoic acid and glycine ethyl ester hydrochloride (Aldrich) according to the method described in Example 1.1/d.

Sources & evidence

ORD record
ord-433aefd47a75447a94efad8b5b9dd54f
Source dataset
uspto-grants-2013_07
Patent number
US08481527B2

Reaction notes

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