Glycine ethyl ester, hydrochloride → HCID 68494533, compound

HRID 446868Notes

Reaction equation

HRID 446868 reaction equation
[Cl:1][C:2]1[CH:27]=[C:26]([F:28])[CH:25]=[CH:24][C:3]=1[O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][S:12]([C:15]1[CH:23]=[CH:22][C:18]([C:19]([OH:21])=O)=[CH:17][CH:16]=1)(=[O:14])=[O:13].Cl.[CH2:30]([O:32][C:33](=[O:36])[CH2:34][NH2:35])[CH3:31]>>[CH2:30]([O:32][C:33](=[O:36])[CH2:34][NH:35][C:19](=[O:21])[C:18]1[CH:22]=[CH:23][C:15]([S:12](=[O:14])(=[O:13])[NH:11][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]2[CH:24]=[CH:25][C:26]([F:28])=[CH:27][C:2]=2[Cl:1])=[CH:16][CH:17]=1)[CH3:31]

Participants

3

Reactant 2

HCID 2723640Glycine ethyl ester, hydrochlorideHCID 68495447HCID 68495447, compound

Product 1

HCID 68494533HCID 68494533, compound

Procedure

The title compound was prepared from 4-[2-(2-chloro-4-fluoro-phenoxy)-phenylsulfamoyl]-benzoic acid and glycine ethyl ester hydrochloride according to the method described in Example 1.1/d.

Sources & evidence

ORD record
ord-628a210944c74a35b33e4858c9c069c7
Source dataset
uspto-grants-2013_07
Patent number
US08481527B2

Reaction notes

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