tert-Butyl piperazine-1-carboxylate → HCID 68579619, compound

HRID 446886Notes

Reaction equation

HRID 446886 reaction equation
[Br:1][C:2]1[CH:31]=[CH:30][C:5]([O:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH:13][S:14]([C:17]2[CH:29]=[CH:28][C:20]([C:21]([NH:23][CH2:24][C:25]([OH:27])=O)=[O:22])=[CH:19][CH:18]=2)(=[O:16])=[O:15])=[C:4]([Cl:32])[CH:3]=1.C(OC([N:40]1[CH2:45][CH2:44][NH:43][CH2:42][CH2:41]1)=O)(C)(C)C>>[ClH:32].[Br:1][C:2]1[CH:31]=[CH:30][C:5]([O:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH:13][S:14]([C:17]2[CH:18]=[CH:19][C:20]([C:21]([NH:23][CH2:24][C:25](=[O:27])[N:40]3[CH2:45][CH2:44][NH:43][CH2:42][CH2:41]3)=[O:22])=[CH:28][CH:29]=2)(=[O:16])=[O:15])=[C:4]([Cl:32])[CH:3]=1

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 68492210HCID 68492210, compound

Product 1

HCID 68579619HCID 68579619, compound

Procedure

The title compound was prepared from {4-[2-(4-bromo-2-chloro-phenoxy)-phenylsulfamoyl]-benzoylamino}-acetic acid (Example 10.1/e) and piperazine-1-carboxylic acid tert-butyl ester (Aldrich) according to the method described in Example 11.1. MS (EI) 609.2 (MH+).

Sources & evidence

ORD record
ord-b2f3042c432c4c05ac55b2c0681f1ecd
Source dataset
uspto-grants-2013_07
Patent number
US08481527B2

Reaction notes

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