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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 447090Generated: October 31, 2026

Methyl 5-chloropyrazine-2-carboxylate → HCID 59191557, compound

https://huagongshe.com/reaction/447090

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 5-chloropyrazine-2-carboxylateHCID 406081—
ReactantHCID 59191468HCID 59191468—
ProductHCID 59191557HCID 5919155756%

Reaction Steps

According to the protocol described below for example 46, 4,5-dimethyl-3-((R)-3-methyl-piperazin-1-yl)-6-pyridin-4-ylmethyl-pyridazine (155 mg, 0.51 mmol) and 5-chloro-pyrazine-2-carboxylic acid methyl ester (99 mg, 0.56 mmol) afforded the title compound as an orange oil (123 mg, 56%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481542B2
Source datasetuspto-grants-2013_07
ORD IDord-aafc920c996143de9f421d81cb27e569
Source noteuspto-grants-2013_07