Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 447107Generated: October 29, 2026

1,4-dichloro-5H,6H,7H-cyclopenta[d]pyridazine → 1-Chloro-4-(4-fluoro-benzyl)-6,7-dihydro-5H-cyclopenta[d]pyridazine

https://huagongshe.com/reaction/447107

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-dichloro-5H,6H,7H-cyclopenta[d]pyridazineHCID 15401908—
ReactantHCID 178505763HCID 178505763—
Product1-Chloro-4-(4-fluoro-benzyl)-6,7-dihydro-5H-cyclopenta[d]pyridazineHCID 59191492—

Reaction Steps

Compound 45 is prepared analogous to compound 44 starting from of 1,4-dichloro-6,7-dihydro-5H-cyclopenta[d]pyridazine (compound 39) and para-fluorobenzyl zinc bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481542B2
Source datasetuspto-grants-2013_07
ORD IDord-5dcdefd00fcc4ea39ccef61603fef065
Source noteuspto-grants-2013_07