HCID 47453722, compound → HCID 15176215, compound

HRID 447142Notes

Reaction equation

HRID 447142 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[NH:10][CH2:11][CH2:12][NH:13]C(=O)OC(C)(C)C>O1CCOCC1>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[NH:10][CH2:11][CH2:12][NH2:13]

Participants

3

Reactant 1

HCID 47453722HCID 47453722, compound

Product 1

HCID 15176215HCID 15176215, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

tert-Butyl 2-(benzo[d]thiazol-2-ylamino)ethylcarbamate (597.7 mgs, 2.04 mmol) was dissolved in 1,4-dioxane (6 mL) then treated with 4N HCL in 1,4-dioxane (6 mL) and stirred for 3 h. A white separated solid was collected by filtration, washed with diethyl ether and dried in vacuum oven overnight at room temperature to yield the hydrochloride salt of N1-(benzo[d]thiazol-2-yl)ethane-1,2-diamine as an off-white amorphous solid.

Workup

  1. customA white separated solid
  2. filtrationwas collected by filtration
  3. washwashed with diethyl ether
  4. customdried in vacuum oven overnight at room temperature

Sources & evidence

ORD record
ord-6af5e80e2608445e82a4cd1801c1a250
Source dataset
uspto-grants-2013_07
Patent number
US08481547B2

Reaction notes

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