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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 447179Generated: October 27, 2026

2-Fluoro-4-iodopyridine → 2-Fluoro-4-[1-(4-fluoro-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

https://huagongshe.com/reaction/447179

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-iodopyridineHCID 7023570—
Reactant4-Ethynyl-1-(4-fluorophenyl)-2-methyl-1H-imidazoleHCID 11665595—
Product2-Fluoro-4-[1-(4-fluoro-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridineHCID 11162227—

Reaction Steps

The title compound, MS: m/e=296.1 (M+H+), was prepared in accordance with the general method of example 1 from 4-ethynyl-1-(4-fluoro-phenyl)-2-methyl-1H-imidazole and 2-fluoro-4-iodopyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481548B2
Source datasetuspto-grants-2013_07
ORD IDord-7b73b4c3686649b0b96b8e327cbfd94d
Source noteuspto-grants-2013_07